SCHEMBL489010

SCHEMBL489010

Cc1ccc(C(=O)O)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.61
NOTUM Q6P988 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
RARB P10826 2/20 0.45
RARA P10276 1/20 0.45
RARG P13631 1/20 0.45
GFER P55789 1/20 0.45
DHODH Q02127 2/20 0.44
MCL1 Q07820 1/20 0.44
SORT1 Q99523 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
KDM4E B2RXH2 1/20 0.44
METAP2 P50579 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28164754 0.98 CSNK2A1 (0.59) CSNK2A1NOTUMMEN1KMT2AALDH1A1
SCHEMBL31011348 0.87 CSNK2A1 (0.61) CSNK2A1NOTUMMEN1KMT2AALDH1A1
SCHEMBL87104 0.87 CSNK2A1 (0.61) CSNK2A1NOTUMMEN1KMT2AALDH1A1
SCHEMBL5597538 0.85 CSNK2A1 (0.59) CSNK2A1NOTUMMEN1KMT2AALDH1A1
SCHEMBL9726681 0.84 CSNK2A1 (0.47) CSNK2A1MEN1KMT2AALDH1A1LOXL2
SCHEMBL10052771 0.84 MCL1 (0.61) CSNK2A1RARBRARARARGMCL1
SCHEMBL467550 0.84 CSNK2A1 (0.68) CSNK2A1NOTUMMEN1KMT2AALDH1A1
SCHEMBL31627797 0.84 CSNK2A1 (0.68) CSNK2A1NOTUMMEN1KMT2AALDH1A1
SCHEMBL29688899 0.83 KMT2A (0.46) CSNK2A1MEN1KMT2AALDH1A1LOXL2
SCHEMBL1226712 0.83 KMT2A (0.46) CSNK2A1MEN1KMT2AALDH1A1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507159-B Preparation method of 4- [3 (E) -pentene-1-yl ] benzoate liquid crystal monomer 中节能万润股份有限公司 2024-05-03 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-116396159-A Synthesis method of 2,2' -biphenyl dicarboxylic acid compound 湖南大学 2023-07-07 CN claimed
CN-114685536-B Binuclear cadmium complex with anticancer activity and preparation method and application thereof 中山职业技术学院 2022-09-02 CN claimed
CN-114507159-A Preparation method of 4- [3(E) -penten-1-yl ] benzoate liquid crystal monomer 中节能万润股份有限公司 2022-05-17 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
CN-110903182-A Simple and environment-friendly chemical synthesis method of 4-fluoro-2-methylbenzoic acid 北京艾德旺科技发展有限公司 2020-03-24 CN claimed
CN-110903176-A Chemical synthesis method of 4-fluoro-2-methylbenzoic acid 北京艾德旺科技发展有限公司 2020-03-24 CN claimed
CN-110343070-A A kind of Antitubulin and the preparation method and application thereof 山东大学 2019-10-18 CN claimed
CN-110088108-A SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS 利奥制药有限公司 2019-08-02 CN claimed
CN-109438418-A Apoptosis signal regulating kinase inhibitor 吉利德科学公司 2019-03-08 CN claimed
CN-122059926-A Heterocyclic degradation determinants for target protein degradation C4医药公司 2026-05-19 CN disclosed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
WO-2025224249-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS AG (CH) 2025-10-30 WO disclosed
US-20250282746-A1 HALOGEN-SUBSTITUTED ISOINDOLINE COMPOUND AND USE THEREOF Chengdu Fendi Pharmaceutical Co., Ltd. (CN) 2025-09-11 US disclosed
CN-1214048-A Benzopyran derivatives having leukotriene-antagonistic action LABROATORIOS MENARINI S A (ES) 1999-04-14 CN disclosed
EP-0061907-B1 SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE BEECHAM GROUP PLC (GB) 1984-08-01 EP disclosed
EP-0061907-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1982-10-06 EP disclosed
US-4046905-A Anti-inflammatory, analgesic and antipyretic phenylacetic acids MERCK & CO., INC. (US) 1977-09-06 US disclosed
US-3947582-A Phenylacetic acid compounds in treating abnormal platelet aggregation MERCK & CO., INC. (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282746-A1 HALOGEN-SUBSTITUTED ISOINDOLINE COMPOUND AND USE THEREOF FLI1, CYP3A7, GTF2I CSNK2A1 1544/4885NOTUM 2086/4885MEN1 1705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.