Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356226 | 0.81 | ALDH1A1 (0.61) | CHRNA7NAMPTCYP2A6DRD2DRD3 | |
| SCHEMBL5516018 | 0.77 | MAPT (0.58) | CHRNA7NAMPTCYP2A6HDAC1ALDH1A1 | |
| SCHEMBL844336 | 0.77 | BCL2L1 (0.53) | CHRNA7NAMPTCYP2A6ALDH1A1KDM4E | |
| SCHEMBL5531762 | 0.76 | ALDH1A1 (0.56) | CHRNA7NAMPTALDH1A1MAPTKDM4E | |
| SCHEMBL28885145 | 0.76 | HDAC1 (0.68) | CHRNA7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5235524 | 0.75 | CYP2A6 (0.51) | CHRNA7NAMPTCYP2A6ALDH1A1POLB | |
| SCHEMBL15194378 | 0.75 | CYP2A6 (0.51) | CHRNA7NAMPTCYP2A6DRD2DRD3 | |
| SCHEMBL1098501 | 0.75 | HPGD (0.54) | CHRNA7NAMPTCYP2A6DRD2DRD3 | |
| SCHEMBL27613491 | 0.74 | CYP2A6 (0.50) | CHRNA7NAMPTCYP2A6ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL27655726 | 0.74 | CYP2A6 (0.50) | CHRNA7NAMPTCYP2A6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | claimed |
| EP-3665169-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | Forma Therapeutics, Inc. (US) | 2020-06-17 | — | — | EP | disclosed |
| WO-2019032863-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-02-14 | — | — | WO | disclosed |
| US-20080306107-A1 | Compounds | ASTRAZENECA AB (SE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | USP28, USP25, USP24 | CHRNA7 4359/4885NAMPT 1718/4885CYP2A6 2374/4885 |
| US-20080306107-A1 | Compounds | FURIN, PCSK9, SLC10A1 | CHRNA7 3256/4885NAMPT 750/4885CYP2A6 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.