SCHEMBL4890424

SCHEMBL4890424

Cc1cccc2c1=NC(C)(NC(=O)O)N=2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
HPGD P15428 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 1/20 0.33
POLB P06746 3/20 0.31
LMNA P02545 2/20 0.30
CYP3A4 P08684 2/20 0.30
MEN1 O00255 1/20 0.30
AKR1B10 O60218 1/20 0.30
TRPA1 O75762 1/20 0.30
ABCB11 O95342 1/20 0.30
DHFR P00374 1/20 0.30
MPO P05164 1/20 0.30
CYP1A2 P05177 1/20 0.30
CHRM1 P11229 1/20 0.30
CYP2C9 P11712 1/20 0.30
AKR1B1 P15121 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL966475 0.83 SMN1; SMN2 (0.34) ALDH1A1HPGDKDM4EHSD17B10LMNA
SCHEMBL4888624 0.77 MAPT (0.34) ALDH1A1HPGDKDM4EHSD17B10POLB
Phosphoric Acid SCHEMBL11599912 0.77 SMN1; SMN2 (0.33) ALDH1A1HPGDKDM4EHSD17B10POLB
SCHEMBL11440168 0.77 ALDH1A1 (0.34) ALDH1A1HPGDKDM4EHSD17B10CYP3A4
SCHEMBL27395123 0.74 KMT2A (0.34) ALDH1A1KDM4EPOLBMEN1CYP1A2
SCHEMBL27731706 0.74 COMT (0.33) ALDH1A1POLBCYP1A2MAPTMAPK1
SCHEMBL6369850 0.69 SMN1; SMN2 (0.38) ALDH1A1HPGDKDM4EHSD17B10MAPT
SCHEMBL28138850 0.68 TSHR (0.31) ALDH1A1
SCHEMBL1678043 0.67 L3MBTL1 (0.43) ALDH1A1HPGDPOLBMEN1CYP1A2
SCHEMBL11838701 0.66 MEN1 (0.38) ALDH1A1HPGDKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101980865-A Hydrophilic member, fin member, aluminum fin member, heat exchanger and air conditioner FUJIFILM CORP 2011-02-23 CN disclosed
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat IDEMITSU TECHNOFINE CO., LTD. (JP) 2008-06-12 US disclosed
EP-1779727-A1 ANTIBACTERIAL COMPOSITION, ANTIBACTERIAL MOLDING, SOLUTION CONTAINING ANTIBACTERIAL COMPOSITION, DETERGENT, SURFACE OF TATAMI MAT AND TATAMI MAT Idemitsu Technofine Co. Ltd (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat TPMT, KAT5, CARM1 ALDH1A1 1896/4885HPGD 3744/4885KDM4E 493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.