Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.59 |
| ▸ | PPARG | P37231 | 12/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963103 | 1.00 | PPARA (0.59) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL3968108 | 0.86 | PPARA (0.60) | PPARAPPARGPPARDADAMTS5 | |
| SCHEMBL3967493 | 0.86 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL16082992 | 0.82 | KMT2A (0.66) | MEN1KMT2AADAMTS5SGMS1 | |
| SCHEMBL3969064 | 0.81 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL4984036 | 0.80 | PTPN1 (0.62) | PPARAPPARGPPARD | |
| SCHEMBL5721665 | 0.80 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL4901621 | 0.79 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL3963614 | 0.79 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL14470660 | 0.79 | PTPN1 (0.67) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462644-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2008-12-09 | — | — | US | claimed |