Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899632 | 1.00 | KIF11 (0.38) | KIF11FFAR1MAPTTP53SMN1; SMN2 | |
| SCHEMBL5886628 | 0.80 | HSD17B10 (0.44) | MAPTSMN1; SMN2LMNA | |
| SCHEMBL4801273 | 0.80 | HSD17B10 (0.44) | MAPTSMN1; SMN2LMNA | |
| SCHEMBL4595123 | 0.77 | KIF11 (0.38) | KIF11FFAR1TDP2SLC6A2P2RY14 | |
| SCHEMBL4596438 | 0.77 | KIF11 (0.38) | KIF11FFAR1TDP2SLC6A2P2RY14 | |
| Trifluoroacetic Acid SCHEMBL4890663 | 0.73 | KIF11 (0.43) | KIF11FFAR1TP53TDP2P2RY14 | |
| Trifluoroacetic Acid SCHEMBL4899626 | 0.73 | KIF11 (0.43) | KIF11FFAR1TP53TDP2P2RY14 | |
| SCHEMBL14154396 | 0.72 | KIF11 (0.48) | KIF11FFAR1TDP2 | |
| SCHEMBL7668861 | 0.68 | GAA (0.34) | MAPTSMN1; SMN2 | |
| SCHEMBL4596362 | 0.64 | KIF11 (0.61) | KIF11TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | claimed |
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | KIF11 562/4885FFAR1 4414/4885MAPT 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.