Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941586 | 1.00 | RAB9A (0.62) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL3433722 | 0.86 | KDM4E (0.55) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL5051826 | 0.86 | KDR (0.68) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL27255927 | 0.84 | CYP19A1 (0.62) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL10937804 | 0.84 | MAPT (0.67) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| Benzene SCHEMBL27629233 | 0.84 | RAB9A (0.69) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| Methane SCHEMBL28704887 | 0.84 | KDR (0.66) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL11097070 | 0.83 | MAPT (0.51) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL31053118 | 0.81 | FFAR1 (0.54) | RAB9AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL1459848 | 0.81 | CYP19A1 (0.61) | RAB9AKDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253300-B | Bisindole compound and preparation method and application thereof | 济南大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-111253300-A | Bisindole compound and preparation method and application thereof | 济南大学 | 2020-06-09 | — | — | CN | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-20150272928-A1 | INDOLE DERIVATIVES | UNIVERSITY OF CENTRAL LANCASHIRE (GB) | 2015-10-01 | — | — | US | disclosed |
| US-20080039625-A1 | Screening Methods | LAUTENS MARK | 2008-02-14 | — | — | US | disclosed |
| US-20080039625-A1 | Screening Methods | LAUTENS MARK | 2008-02-14 | — | — | US | disclosed |
| US-20080039625-A1 | Screening Methods | LAUTENS MARK | 2008-02-14 | — | — | US | disclosed |
| EP-1817283-A1 | 2-SUBSTITUTED INDOLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | Lautens, Mark (CA) | 2007-08-15 | — | — | EP | disclosed |
| EP-1390340-A4 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-07-25 | — | — | EP | disclosed |
| CN-1286810-C | 2-acyl indol derivatives and their use as anti-tumour agents | BAKST HEALTH AG (CH) | 2006-11-29 | — | — | CN | disclosed |
| EP-1463744-A4 | DEVICES AND METHODS FOR ISOLATING AND DETECTING SPECIFIC SUBSTANCES IN COMPLEX MATRICES | SAFETEST INC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1463744-A2 | DEVICES AND METHODS FOR ISOLATING AND DETECTING SPECIFIC SUBSTANCES IN COMPLEX MATRICES | Safetest, Inc. (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1390340-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-02-25 | — | — | EP | disclosed |
| US-20030148354-A1 | Devices and methods for isolating and detecting specific substances in complex matrices | SAFTEST, INC. (US) | 2003-08-07 | — | — | US | disclosed |
| CN-1431997-A | 2-acylindole derivatives and their use as antitumor agents | BAKST HEALTH AG (CH) | 2003-07-23 | — | — | CN | disclosed |
| WO-2003054516-A2 | DEVICES AND METHODS FOR ISOLATING AND DETECTING SPECIFIC SUBSTANCES IN COMPLEX MATRICES | SAFETEST, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
| WO-2002085838-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-31 | — | — | WO | disclosed |
| EP-0362695-A1 | Pyrrolocarbazole derivatives, processes for their preparation and their use as medicaments | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-04-11 | — | — | EP | disclosed |
| US-4045458-A | FRIEDEL-CRAFTS CATALYSTS | KANZAKI PAPER MANUFACTURING CO., LTD. (JA) | 1977-08-30 | — | — | US | disclosed |
| US-4022802-A | INDOLES, ALKALI HYDROXIDE; ALKYLATION | CIBA-GEIGY AG (CH) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039625-A1 | Screening Methods | CBR3, ZKSCAN2, CRBN | RAB9A 444/4885KDM4E 3829/4885MAPT 4661/4885 |
| US-20150272928-A1 | INDOLE DERIVATIVES | IDO1, TPH1, IDO2 | RAB9A 3326/4885KDM4E 572/4885MAPT 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.