Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78460 | 1.00 | FFAR1 (0.43) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL78175 | 0.95 | ALDH1A1 (0.42) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7039463 | 0.89 | GBA1 (0.39) | FFAR1POLBL3MBTL1KDM4EMEN1 | |
| SCHEMBL27690561 | 0.83 | FFAR1 (0.43) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL21135743 | 0.83 | FFAR1 (0.46) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL21136648 | 0.83 | FFAR1 (0.46) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL21135457 | 0.83 | FFAR1 (0.58) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL21135481 | 0.83 | FFAR1 (0.58) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL1584946 | 0.83 | FFAR1 (0.43) | FFAR1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL1584947 | 0.83 | FFAR1 (0.43) | FFAR1CCNE2CDK4CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114007-A1 | 5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-15 | — | — | US | disclosed |
| EP-0962452-B1 | Oxidative hair dye compositions and methods containing 1-(4-aminophenyl)-2-pyrrolidinemethanols | P & G CLAIROL INC (US) | 2003-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114007-A1 | 5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | FLT3, FES, ALK | FFAR1 621/4885CCNE2 675/4885CDK4 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.