Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4890984 | 0.89 | FFAR1 (0.43) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL78460 | 0.89 | FFAR1 (0.43) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL78175 | 0.88 | ALDH1A1 (0.42) | GBA1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL7452343 | 0.78 | GFER (0.33) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL188824 | 0.78 | GFER (0.46) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL15651450 | 0.78 | MTOR (0.41) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL13735239 | 0.78 | MTOR (0.41) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL189033 | 0.78 | GFER (0.46) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL22471285 | 0.78 | GFER (0.46) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL7100773 | 0.77 | GBA1 (0.52) | GBA1MAPTALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028976-A1 | Compositions for dyeing keratinic fibres, containing paraphenylenediamine derivatives with an azetidinyl group | KRT18, CDC73, AOC1 | GBA1 4322/4885MAPT 1146/4885ALDH1A1 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.