Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437699 | 0.98 | DGKA (0.50) | DGKALMNATSHRPAMMAPT | |
| SCHEMBL8812664 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL5930620 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL11264807 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL11266899 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL10889536 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL10892398 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL21956085 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL17440355 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT | |
| SCHEMBL6438468 | 0.92 | DGKA (0.53) | DGKALMNATSHRMAPTTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167373-A1 | Production of Furanones | UNISEARCH LIMITED, A.C.N. (AU) | 2008-07-10 | — | — | US | disclosed |
| US-7378535-B2 | intermediate for side chain functionalization of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones); 4-Bromo-5(bromomethylene)-3-(1-bromoethyl)-2(5H)-furanone from N-bromosuccinimide the 3-ethylfuranone | UNISEARCH LIMITED, A.C.N. (AU) | 2008-05-27 | — | — | US | disclosed |
| EP-1787988-A2 | Production of furanones | Biosignal Australia Pty Limited (AU) | 2007-05-23 | — | — | EP | disclosed |
| US-20070032666-A1 | Production of furanones | UNISEARCH LIMITED, A.C.N. (AU) | 2007-02-08 | — | — | US | disclosed |
| EP-1071677-B1 | PRODUCTION OF FURANONES | BIOSIGNAL AUSTRALIA PTY LTD (AU) | 2007-02-07 | — | — | EP | disclosed |
| US-7064220-B1 | Production of furanones | UNISEARCH LIMITED, A.C.N. (AU) | 2006-06-20 | — | — | US | disclosed |
| EP-1071677-A4 | PRODUCTION OF FURANONES | UNISEARCH LTD (AU) | 2003-04-02 | — | — | EP | disclosed |
| EP-1071677-A1 | PRODUCTION OF FURANONES | UNISEARCH LIMITED (AU) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054323-A1 | PRODUCTION OF FURANONES | UNISEARCH LIMITED (AU) | 1999-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032666-A1 | Production of furanones | PFAS, FASN, STS | DGKA 3295/4885LMNA 3027/4885TSHR 3994/4885 |
| US-20080167373-A1 | Production of Furanones | PFAS, FASN, STS | DGKA 3295/4885LMNA 3027/4885TSHR 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.