Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891040 | 1.00 | LMNA (0.52) | LMNATRPA1NOS3NOS2MIF | |
| SCHEMBL25620436 | 0.83 | LMNA (0.45) | LMNATRPA1NOS3NOS2MIF | |
| SCHEMBL27598358 | 0.80 | LMNA (0.38) | LMNATRPA1AOC3GAAMAPK1 | |
| SCHEMBL28897926 | 0.80 | LMNA (0.38) | LMNATRPA1AOC3GAAMAPK1 | |
| SCHEMBL28396668 | 0.78 | EPHX1 (0.42) | TRPA1 | |
| SCHEMBL9245432 | 0.76 | LMNA (0.47) | LMNATRPA1NOS3NOS2MIF | |
| SCHEMBL27640130 | 0.76 | ACP3 (0.45) | — | |
| SCHEMBL28607657 | 0.74 | LMNA (0.48) | LMNATRPA1NOS3NOS2MIF | |
| SCHEMBL3144258 | 0.74 | LMNA (0.48) | LMNATRPA1NOS3NOS2MIF | |
| SCHEMBL1254320 | 0.73 | LMNA (0.48) | LMNATRPA1NOS3NOS2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080222754-A1 | Methods of Modulating Glucosinolate Production in Plants | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-09-11 | — | — | US | disclosed |
| US-20050223431-A1 | Methods of modulating glucosinolate production in plants | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, AN ARIZONA CORPORATION. | 2005-10-06 | — | — | US | disclosed |
| EP-0417167-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | AlliedSignal Inc. (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989011473-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | ALLIED-SIGNAL INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| EP-0158159-B1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS AND THE CONVERSION THEREOF INTO THE CORRESPONDING HYDROXYLAMINE O-SUBSTITUTED | AlliedSignal Inc. (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4614813-A | Process for the preparation of N-hydroxy organo imidate compounds | ALLIED CORPORATION (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0158153-A2 | Process for the preparation of N-hydroxy organo imidate compounds | ALLIED CORPORATION (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0158159-A1 | Process for the synthesis of o-substituted oxime compounds and the conversion thereof into the corresponding hydroxylamine o-substituted | AlliedSignal Inc. (US) | 1985-10-16 | — | — | EP | disclosed |