Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796011 | 0.91 | CNR1 (0.36) | CNR1CNR2 | |
| SCHEMBL4600601 | 0.84 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL4886146 | 0.84 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4886166 | 0.84 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4599472 | 0.83 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4599841 | 0.83 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL4599048 | 0.81 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL4885391 | 0.80 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL4600693 | 0.80 | ALPL (0.33) | CNR1CNR2EPAS1 | |
| SCHEMBL4923174 | 0.79 | CNR1 (0.42) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287517-A1 | Pyrazole Derivatives as Cb1 Modulators | ASTRAZENECA AB (SE) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287517-A1 | Pyrazole Derivatives as Cb1 Modulators | CNR1, CNR2, HTR3C | CNR1 1/4885CNR2 2/4885EPAS1 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.