Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778254 | 0.85 | S1PR1 (0.38) | S1PR1BACE1KMT2ANPC1RAB9A | |
| SCHEMBL9977870 | 0.83 | CYP1A2 (0.39) | S1PR1BACE1NPSR1KMT2ANPC1 | |
| SCHEMBL19863784 | 0.79 | NPSR1 (0.58) | S1PR1NPSR1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL13497675 | 0.79 | S1PR1 (0.53) | S1PR1BACE1NPY5RNPSR1KMT2A | |
| SCHEMBL25171851 | 0.71 | CYP1A2 (0.59) | S1PR1BACE1NPY5RKMT2ANPC1 | |
| SCHEMBL22090002 | 0.71 | KMT2A (0.42) | S1PR1BACE1NPY5RKMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL31258765 | 0.70 | CYP1A2 (0.57) | S1PR1BACE1NPY5RKMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL25167011 | 0.70 | CYP1A2 (0.57) | S1PR1BACE1NPY5RKMT2ANPC1 | |
| SCHEMBL14336554 | 0.69 | S1PR1 (0.41) | S1PR1BACE1NPY5RNPSR1KMT2A | |
| SCHEMBL4891923 | 0.68 | LMNA (0.47) | S1PR1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | S1PR1 3106/4885BACE1 4489/4885NPY5R 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.