Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Allylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allylamine SCHEMBL5182623 | 1.00 | — | — | |
| Allylamine SCHEMBL9422863 | 0.87 | — | — | |
| Allylamine SCHEMBL10528352 | 0.85 | — | — | |
| Allylamine SCHEMBL3921566 | 0.85 | — | — | |
| Allylamine SCHEMBL371327 | 0.81 | — | — | |
| Allylamine SCHEMBL8774885 | 0.81 | — | — | |
| Allylamine SCHEMBL27908618 | 0.81 | — | — | |
| Allylamine SCHEMBL18302510 | 0.81 | — | — | |
| Allylamine SCHEMBL7599092 | 0.81 | — | — | |
| Allylamine SCHEMBL3980116 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-10-05 | — | — | US | disclosed |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | disclosed |
| US-20230270648-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | disclosed |
| US-20230270649-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | disclosed |
| US-20080279803-A1 | Method and Composition for Restructuring Keratin Fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-11-13 | — | — | US | disclosed |
| US-20030148912-A1 | Detergent and cleaning agent shaped bodies wih improved disintegration properties | COGNIS DEUTSCHLAND GMBH & CO. KG (DE) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279803-A1 | Method and Composition for Restructuring Keratin Fibers | KRT18, CBR3, CBR1 | ALDH1A1 1331/4885TSHR 3606/4885TP53 3135/4885 |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, COX5A | ALDH1A1 28/4885TSHR 4771/4885TP53 2515/4885 |
| US-20230270649-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, COX5A | ALDH1A1 37/4885TSHR 4846/4885TP53 2746/4885 |
| US-20230270648-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, ALDH2 | ALDH1A1 26/4885TSHR 4819/4885TP53 2362/4885 |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, ALDH2 | ALDH1A1 40/4885TSHR 4836/4885TP53 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.