Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649679 | 0.83 | POLB (0.45) | HTTTSHRPOLBTDP1LMNA | |
| SCHEMBL4650297 | 0.71 | TDP1 (0.47) | POLBTDP1LMNAPKMALDH1A1 | |
| SCHEMBL4822180 | 0.69 | PTPN1 (0.46) | POLBCYP3A4CYP2C19 | |
| SCHEMBL15564948 | 0.68 | HTT (0.55) | HTTTSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL4649758 | 0.68 | POLB (0.46) | POLBKDM4ETDP1LMNAPKM | |
| SCHEMBL4573235 | 0.66 | ACE (0.61) | POLBKDM4ETDP1LMNAALDH1A1 | |
| SCHEMBL8908771 | 0.66 | ACE (0.61) | POLBKDM4ETDP1LMNAALDH1A1 | |
| SCHEMBL3840630 | 0.66 | ACE (0.61) | POLBKDM4ETDP1LMNAALDH1A1 | |
| SCHEMBL9596147 | 0.65 | POLB (0.65) | POLBTDP1LMNAPKMALDH1A1 | |
| SCHEMBL25380410 | 0.65 | PREP (0.50) | GAAMEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904495-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007281-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |