Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156019 | 0.79 | MAPT (0.52) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL29580092 | 0.77 | MAPT (0.50) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL10936934 | 0.77 | MAPT (0.50) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL202616 | 0.77 | ADRA2A (0.55) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL14450630 | 0.76 | MAPT (0.49) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL180816 | 0.76 | MAPT (0.49) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL295867 | 0.76 | SLC2A1 (0.53) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL5473 | 0.76 | KMT2A (0.50) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL18403105 | 0.76 | MAPT (0.49) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL16289876 | 0.76 | MAPT (0.49) | MAPTADRA2AADRA2BADRA2CSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2975040-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | Sagami Chemical Research Institute (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-7425568-B2 | Compounds, which are potent inhibitors of Na+ /Ca2+ exchange mechanism and are useful in the treatment of arrhythmias | ORION CORPORATION (FI) | 2008-09-16 | — | — | US | disclosed |
| US-20080063977-A1 | Method of increasing speed of silver halide color photosensitive material | FUJIFILM CORPORATION | 2008-03-13 | — | — | US | disclosed |
| US-7153638-B2 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-7115356-B2 | Extremely high image quality excelling in graininess and in bright acuity; 5-membered azole ring containing 2 to 4 nitrogen atoms; a a heterocyclic ring having one or two heteroatoms including the nitrogen atom; red, green and blue sensitive | FUJI PHOTO FILM CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| EP-1412343-B1 | COMPOUNDS, WHICH ARE POTENT INHIBITORS OF NA+/CA2+ EXCHANGE MECHANISM AND ARE USEFUL IN THE TREATMENT OF ARRHYTHMIAS | ORION CORP (FI) | 2006-08-30 | — | — | EP | disclosed |
| US-7074550-B2 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1041438-B1 | Silver halide photographic light-sensitive material, heterocyclic azo dye forming compound, and method of preparing dye | FUJI PHOTO FILM CO LTD (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20030175627-A1 | Method of increasing speed of silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. | 2003-09-18 | — | — | US | disclosed |
| CN-1115334-C | Pyridine derivative and medicine containing the same | OTSUKA PHARMA CO LTD (JP) | 2003-07-23 | — | — | CN | disclosed |
| US-6518006-B2 | Yellow-developing photosensitive silver halide emulsion layer on a support contains one dye-forming coupler, and nonphotosensitive hydrophilic colloid layers contain dispersion of dye; sharpness, high strength | FUJI PHOTO FILM CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| WO-2003006452-A1 | NEW COMPOUNDS, WHICH ARE POTENT INHIBITORS OF NA+/CA2+ EXCHANGE MECHANISM AND ARE USEFUL IN THE TREATMENT OF ARRHYTHMIAS | ORION CORPORATION (FI) | 2003-01-23 | — | — | WO | disclosed |
| US-20020048733-A1 | Silver Halide color photographic photosensitive material | FUJIFILM CORPORATION (JP) | 2002-04-25 | — | — | US | disclosed |
| EP-0831368-B1 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6200742-B1 | EXCELLENT COLOR REPRODUCIBILITY, SHARPNESS AND COLORFASTNESS BY INCLUDING IN THE LIGHT SENSITIVE MATERIAL A COUPLER (A FUSED 1,2,4-OXADIAZOLE RING) THAT PROVIDES AN AZO DYE HAVING EXCELLENT HUES, LARGE MOLAR EXTINCTION COEFFICIENT; STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| EP-1041438-A1 | Silver halide photographic light-sensitive material, heterocyclic azo dye forming compound, and method of preparing dye | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-04 | — | — | EP | disclosed |
| US-5948607-A | DYE FORMING COUPLER; EXCELLENT IN COLOR REPRODUCIBILITY, SHARPNESS AND COLOR IMAGE FASTNESS. | FUJI PHOTO FILM CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0831368-A1 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1998-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | MAPT 4308/4885ADRA2A 3534/4885ADRA2B 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.