Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895290 | 0.94 | HPGD (0.38) | ADRB3HPGDNR1I2KEAP1NFE2L2 | |
| SCHEMBL4840597 | 0.91 | ADRB3 (0.37) | ADRB3HPGDNR1I2KEAP1NFE2L2 | |
| SCHEMBL4918960 | 0.90 | ADRB3 (0.38) | ADRB3HPGDNR1I2KEAP1NFE2L2 | |
| SCHEMBL4605628 | 0.90 | ADRB3 (0.42) | ADRB3HPGDNR1I2OPRM1OPRD1 | |
| SCHEMBL4605863 | 0.89 | NR1I2 (0.40) | ADRB3HPGDNR1I2OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL4840585 | 0.89 | ADRB3 (0.41) | ADRB3HPGDNR1I2KEAP1NFE2L2 | |
| SCHEMBL4908161 | 0.88 | NR1I2 (0.41) | ADRB3HPGDNR1I2KEAP1NFE2L2 | |
| SCHEMBL4894128 | 0.88 | ADRB3 (0.42) | ADRB3HPGDNR1I2KEAP1NFE2L2 | |
| SCHEMBL4892553 | 0.88 | ADRB3 (0.38) | ADRB3HPGDNR1I2KEAP1NFE2L2 | |
| SCHEMBL4891889 | 0.88 | ADRB3 (0.36) | ADRB3HPGDNR1I2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269281-A1 | Novel Beta-Agonists, Method for Producing Them and Their Use as Drugs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269281-A1 | Novel Beta-Agonists, Method for Producing Them and Their Use as Drugs | ADRB3, ADRB2, ADRB1 | ADRB3 1/4885HPGD 1587/4885NR1I2 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.