Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889571 | 1.00 | ADRB3 (0.43) | ADRB3NR1I2ALDH1A1NPSR1HPGD | |
| SCHEMBL4892568 | 1.00 | ADRB3 (0.43) | ADRB3NR1I2ALDH1A1NPSR1HPGD | |
| SCHEMBL4894075 | 0.94 | ADRB3 (0.43) | ADRB3NR1I2ALDH1A1NPSR1HPGD | |
| SCHEMBL4775536 | 0.91 | ADRB3 (0.42) | ADRB3NR1I2ALDH1A1HPGDOPRM1 | |
| SCHEMBL4895295 | 0.90 | ADRB3 (0.43) | ADRB3NR1I2ALDH1A1HPGDOPRM1 | |
| SCHEMBL2199546 | 0.90 | ADRB3 (0.43) | ADRB3NR1I2ALDH1A1HPGDOPRM1 | |
| SCHEMBL4916377 | 0.90 | ADRB3 (0.43) | ADRB3NR1I2ALDH1A1HPGDOPRM1 | |
| SCHEMBL4776666 | 0.89 | ADRB3 (0.42) | ADRB3NR1I2ALDH1A1NPSR1HPGD | |
| SCHEMBL4777081 | 0.89 | ADRB3 (0.42) | ADRB3NR1I2ALDH1A1NPSR1HPGD | |
| Trifluoroacetic Acid SCHEMBL4777048 | 0.88 | ADRB3 (0.41) | ADRB3NR1I2ALDH1A1HPGDADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269281-A1 | Novel Beta-Agonists, Method for Producing Them and Their Use as Drugs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | US | claimed |
| US-20080269281-A1 | Novel Beta-Agonists, Method for Producing Them and Their Use as Drugs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269281-A1 | Novel Beta-Agonists, Method for Producing Them and Their Use as Drugs | ADRB3, ADRB2, ADRB1 | ADRB3 1/4885NR1I2 357/4885ALDH1A1 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.