Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817250 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL816899 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL817400 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL3367533 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL816644 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL814710 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL815544 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL406725 | 1.00 | — | — | |
| SCHEMBL816974 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL814959 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119493-A1 | 5,6-Dialkyl-7-Aminotriazolopyrimidines, their Preparation and their Use for Controlling Harmful Fungi, and Compositions Comprising these Compounds | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-22 | — | — | US | claimed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | claimed |
| CN-108475642-A | N-type semiconductor element and compensated semiconductor device and its manufacturing method and use its wireless telecom equipment | 东丽株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-107431096-A | Rectifier cell, its manufacture method and radio communication device | 东丽株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-100477981-C | Composition for applying to skin and skin covering | OREAL L OREAL S A L (FR) | 2009-04-15 | — | — | CN | disclosed |
| US-20080188493-A1 | 5,6-Dialkyl-7-Aminoazolopyrimidines, Their Preparation and Their Use For Controlling Harmful Fungi, and Compositions Comprising These Compounds | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-07 | — | — | US | disclosed |
| US-20080119493-A1 | 5,6-Dialkyl-7-Aminotriazolopyrimidines, their Preparation and their Use for Controlling Harmful Fungi, and Compositions Comprising these Compounds | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-22 | — | — | US | disclosed |
| EP-1856121-A1 | 5,6-DIALKYL-7-AMINO-AZOLOPYRIMIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI AND AGENTS CONTAINING SAID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-21 | — | — | EP | disclosed |
| EP-1725563-A2 | 5,6-DIALKYL-7-AMINO-TRIAZOLOPYRIMIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI AND AGENTS CONTAINING SAID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2006092414-A1 | 5,6-DIALKYL-7-AMINO-AZOLOPYRIMIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI AND AGENTS CONTAINING SAID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-08 | — | — | WO | disclosed |
| CN-1694678-A | Composition for application to the skin and skin covering | OREAL L OREAL S A L (FR) | 2005-11-09 | — | — | CN | disclosed |
| WO-2005087770-A2 | 5,6-DIHYDROCARBYL-7-AMINO-TRIAZOLOPYRIMIDINES, METHOD FOR THEIR PRODUCTION, THEIR USE FOR CONTROLLING PATHOGENIC FUNGI AND AGENTS CONTAINING SAID COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119493-A1 | 5,6-Dialkyl-7-Aminotriazolopyrimidines, their Preparation and their Use for Controlling Harmful Fungi, and Compositions Comprising these Compounds | DPM1, ALKBH5, DERA | TSHR 3758/4885THRB 3385/4885FAAH 3407/4885 |
| US-20080188493-A1 | 5,6-Dialkyl-7-Aminoazolopyrimidines, Their Preparation and Their Use For Controlling Harmful Fungi, and Compositions Comprising These Compounds | HDHD5, AGPS, DPM1 | TSHR 4346/4885THRB 4512/4885FAAH 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.