Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 10/20 | 0.33 |
| ▸ | CA1 | P00915 | 9/20 | 0.33 |
| ▸ | CA7 | P43166 | 7/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.33 |
| ▸ | CA12 | O43570 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.32 |
| ▸ | CA4 | P22748 | 5/20 | 0.32 |
| ▸ | CA5A | P35218 | 4/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.32 |
| ▸ | CA6 | P23280 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207320 | 0.70 | CA2 (0.39) | CA2CA1CA7CA13CA12 | |
| Ammonia Solution, Strong SCHEMBL28243882 | 0.64 | TDP1 (0.39) | CA2CA1CA7CA13CA12 | |
| SCHEMBL28791202 | 0.64 | CA2 (0.43) | BCL2L1CA2CA1CA7CA12 | |
| SCHEMBL25434446 | 0.63 | CA2 (0.44) | BCL2L1CA2CA1CA7CA12 | |
| SCHEMBL6468837 | 0.62 | CA2 (0.38) | BCL2L1CA2CA1CA7CA13 | |
| SCHEMBL17394632 | 0.62 | CA2 (0.38) | CA2CA1CA7CA13CA12 | |
| SCHEMBL10663419 | 0.62 | KMT2A (0.41) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6275260 | 0.62 | CA2 (0.47) | CA2CA1CA7CA13CA12 | |
| SCHEMBL28204304 | 0.62 | TDP1 (0.41) | CA2CA1CA7CA13CA12 | |
| SCHEMBL27775996 | 0.61 | NPY1R (0.43) | CA2CA1CA7CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110691-A1 | NOVEL TRICYCLIC DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2008-09-18 | — | — | WO | disclosed |