Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA4 | P22748 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA3 | P07451 | 4/20 | 0.37 |
| ▸ | CA6 | P23280 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.37 |
| ▸ | CA5A | P35218 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114262 | 0.73 | CA2 (0.40) | CA2CA4CA12CA1CA3 | |
| SCHEMBL6468940 | 0.73 | TDP1 (0.49) | CA2CA12CA1CA9TDP1 | |
| SCHEMBL4215302 | 0.72 | HTT (0.42) | CA2CA4CA12CA1CA3 | |
| SCHEMBL6468791 | 0.67 | TDP1 (0.46) | CA2CA12CA1CA7CA9 | |
| SCHEMBL6470839 | 0.66 | MAPT (0.45) | CA2CA9TDP1MAPTGAA | |
| SCHEMBL1114110 | 0.64 | CA2 (0.36) | CA2CA4CA12CA1CA3 | |
| SCHEMBL4707544 | 0.64 | PDE7A (0.48) | TDP1PDE7APDE7BMAPTGAA | |
| SCHEMBL4893213 | 0.62 | BCL2L1 (0.34) | CA2CA4CA12CA1CA3 | |
| SCHEMBL5013613 | 0.62 | CA2 (0.51) | CA2CA4CA12CA1CA3 | |
| SCHEMBL9709555 | 0.60 | PDE7A (0.58) | TDP1PDE7APDE7BMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |