Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28201987 | 0.98 | AKR1C3 (0.50) | AKR1C3GAAMAPTKEAP1CYP19A1 | |
| SCHEMBL11631691 | 0.89 | NR4A1 (0.58) | ALDH1A1FFAR1L3MBTL1SRD5A2LMNA | |
| SCHEMBL28423359 | 0.88 | AKR1C3 (0.59) | AKR1C3GAAMAPTCYP19A1ALDH1A1 | |
| SCHEMBL7598180 | 0.86 | HMGB1 (0.49) | AKR1C3GAAMAPTKEAP1NR4A2 | |
| SCHEMBL8268149 | 0.86 | SLC16A3 (0.49) | KEAP1ALDH1A1ELANEFFAR1SRD5A2 | |
| SCHEMBL9627316 | 0.86 | MAPT (0.50) | AKR1C3GAAMAPTCYP19A1ALDH1A1 | |
| SCHEMBL9177089 | 0.86 | AKR1C3 (0.48) | AKR1C3GAAMAPTCYP19A1ALDH1A1 | |
| SCHEMBL14259339 | 0.85 | KMT2A (0.56) | KEAP1ALDH1A1FFAR1SRD5A2LMNA | |
| SCHEMBL9715720 | 0.84 | KEAP1 (0.47) | GAAMAPTKEAP1NR4A2ALDH1A1 | |
| SCHEMBL6442157 | 0.84 | CES2 (0.50) | GAAKEAP1NR4A2ALDH1A1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107759466-B | Splitting method of (+/-) -2- (3-benzoyl) -phenylpropionic acid | 浙江瑞博制药有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-107759466-A | The method for splitting of (±) 2 (3 benzoyl) phenylpropionic acid | 浙江瑞博制药有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-102010327-A | Splitting method of (+/-)-2-(3-benzoyl)-phenylpropionic acid | ZHEJIANG JIUZHOU PHARM CO LTD | 2011-04-13 | — | — | CN | claimed |
| US-5191112-A | Salt formation, crystallization | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-02 | — | — | US | claimed |
| EP-0423467-A2 | Method for optical resolution of (+/-)-2-(3-benzoyl)-phenylpropionic acid | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-04-24 | — | — | EP | claimed |
| JP-4069356-A | — | — | None | — | — | JP | disclosed |
| JP-4069356-A | — | — | None | — | — | JP | disclosed |
| CN-107759466-B | Splitting method of (+/-) -2- (3-benzoyl) -phenylpropionic acid | 浙江瑞博制药有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-107759466-A | The method for splitting of (±) 2 (3 benzoyl) phenylpropionic acid | 浙江瑞博制药有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-104546835-A | Application of 3-(benzoyl phenyl) propionic acid derivative in treatment of connexin CX31 mediated skin diseases | TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE | 2015-04-29 | — | — | CN | disclosed |
| CN-102010327-B | Splitting method of (+/-)-2-(3-benzoyl)-phenylpropionic acid | ZHEJIANG JIUZHOU PHARM CO LTD | 2013-04-10 | — | — | CN | disclosed |
| CN-102010327-A | Splitting method of (+/-)-2-(3-benzoyl)-phenylpropionic acid | ZHEJIANG JIUZHOU PHARM CO LTD | 2011-04-13 | — | — | CN | disclosed |
| US-4937375-A | (Phenylethenyl)phenylpropionic acid and its ester, and method for producing (benzoylphenyl)propionic acid or its ester | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-26 | — | — | US | disclosed |
| US-4922052-A | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl) propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0283038-A1 | (Vinylphenyl)phenylmethane and method for producing (benzoylphenyl)propionic acid | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0282066-A2 | (Phenylethenyl) phenylpropionaldehyde and method for producing (benzoylphenyl) propionic acid using the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282065-A2 | (Phenylethenyl) phenylpropionic acid and its ester, and method for producing (benzoylphenyl) propionic acid or its ester | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |
| US-4111997-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL COMPANY, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
| US-4007225-A | ANTIPYRETIC, ANALGESIC, ANTIINFLAMMATORY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-02-08 | — | — | US | disclosed |
| US-3953500-A | ANTIPYRETICS, ANALGESICS, ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-27 | — | — | US | disclosed |