Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729928 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL9717121 | 0.87 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL8009092 | 0.87 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL13876479 | 0.87 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL9081134 | 0.86 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL8350350 | 0.86 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL11327868 | 0.86 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL9081136 | 0.86 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL11327872 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL27581561 | 0.84 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822707-B2 | Nucleophile assisting leaving groups | FLORIDA ATLANTIC UNIVERSITY (US) | 2014-09-02 | — | — | US | disclosed |
| US-20080221347-A1 | Oligoether, crown ether linked to an acyclic or cyclic group linked with a sulfonate or silanol leaving group to an alkyl group, an alkenyl group, an alkynyl group or an optionally substituted aromatic or heteroaryl group; stabilized leaving group is more easily displaced | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-11 | — | — | US | disclosed |
| WO-2006060142-A2 | NUCLEOPHILE ASSISTING LEAVING GROUPS | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221347-A1 | Oligoether, crown ether linked to an acyclic or cyclic group linked with a sulfonate or silanol leaving group to an alkyl group, an alkenyl group, an alkynyl group or an optionally substituted aromatic or heteroaryl group; stabilized leaving group is more easily displaced | OSTC, STS, TST | ALDH1A1 3919/4885TSHR 722/4885LMNA 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.