Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2382039 | 0.78 | — | — | |
| SCHEMBL17633027 | 0.76 | — | — | |
| SCHEMBL2815843 | 0.69 | TSHR (0.38) | TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL12765788 | 0.67 | TSHR (0.33) | TSHR | |
| SCHEMBL14162153 | 0.67 | — | — | |
| Ethylene SCHEMBL1617394 | 0.67 | TSHR (0.37) | TSHRKDM4E | |
| Adamantane SCHEMBL28908472 | 0.66 | CYP2C9 (0.40) | TSHRLMNA | |
| SCHEMBL13018767 | 0.66 | — | — | |
| Adamantane SCHEMBL12761 | 0.66 | CYP2C9 (0.46) | TSHRLMNA | |
| Adamantane SCHEMBL29707714 | 0.66 | CYP2C9 (0.46) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217484-B | Naphthalimide derivative based on methylene adamantane modification as well as preparation method and application thereof | 苏州大学 | 2024-04-05 | — | — | CN | claimed |
| CN-116217484-A | Naphthalimide derivative based on methylene adamantane modification as well as preparation method and application thereof | 苏州大学 | 2023-06-06 | — | — | CN | claimed |
| CN-110770282-A | Curable silicone composition, and application and use thereof | 莫门蒂夫性能材料股份有限公司 | 2020-02-07 | — | — | CN | claimed |
| US-10287400-B2 | Curable silicone composition and applications and uses thereof | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-05-14 | — | — | US | claimed |
| CN-109312077-A | Curable silicon composition and its application and use | 莫门蒂夫性能材料股份有限公司 | 2019-02-05 | — | — | CN | claimed |
| US-20170298188-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2017-10-19 | — | — | US | claimed |
| US-20080051597-A1 | Process for Producing 2-Methyladamantan-2-Yl (Meth)Acrylate and 2-Methyladamantan-2-Yl (Meth)Acrylate | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-02-28 | — | — | US | claimed |
| US-7148363-B2 | Process for preparing acrylate compound | TOSOH CORPORATION (JP) | 2006-12-12 | — | — | US | claimed |
| US-6833462-B2 | Esterification to get cyclic acrylate compounds; used as raw material for functional polymers, pharmaceuticals, pesticides, semiconductor lithography | TOSOH CORPORATION (JP) | 2004-12-21 | — | — | US | claimed |
| EP-1230227-B1 | BENZOXA-AND BENZOTHIAZOLYL SULFAMATES AND THEIR USE AS STEROID SULFATASE INHIBITORS | NOVARTIS AG (CH) | 2004-06-23 | — | — | EP | claimed |
| US-6716865-B1 | SUBSTITUTED AT THE 2 POSITION; A SULFAMATE BOUND VIA OXYGEN TO THE PHENYL PART OF THE RING STRUCTURE; SULFAMOYLATION; STEROID SULFATASE INHIBITOR, ACNE | NOVARTIS AG (CH) | 2004-04-06 | — | — | US | claimed |
| US-20030139613-A1 | Process for preparing acrylate compound | TOSOH CORPORATION | 2003-07-24 | — | — | US | claimed |
| EP-1230227-A1 | BENZOXA-AND BENZOTHIAZOLYL SULFAMATES AND THEIR USE AS STEROID SULFATASE INHIBITORS | Novartis AG (CH) | 2002-08-14 | — | — | EP | claimed |
| WO-2001036398-A1 | BENZOXA- AND BENZTHIAZOLES | NOVARTIS AG (CH) | 2001-05-25 | — | — | WO | claimed |
| EP-3515892-B1 | COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2026-04-15 | — | — | EP | disclosed |
| WO-2025043152-A1 | METHODS OF DEALKENYLATIVE AMINATION AND AZIDATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-27 | — | — | WO | disclosed |
| US-12122730-B2 | Methods of carbon-carbon bond fragmentation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-10-22 | — | — | US | disclosed |
| EP-0554244-A1 | ADAMANTANE POLYMERIC COMPOSITIONS | MOBIL OIL CORPORATION (US) | 1993-08-11 | — | — | EP | disclosed |
| WO-1992007018-A1 | ADAMANTANE POLYMERIC COMPOSITIONS | MOBIL OIL CORPORATION (US) | 1992-04-30 | — | — | WO | disclosed |
| US-5053434-A | Diamondoid polymeric compositions | MOBIL OIL CORPORATION (US) | 1991-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298188-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | VCL, CCNI, SMCHD1 | TSHR 4542/4885KDM4E 2206/4885ALDH1A1 1443/4885 |
| US-20030139613-A1 | Process for preparing acrylate compound | AFF1, AFF4, RER1 | TSHR 994/4885KDM4E 1056/4885ALDH1A1 241/4885 |
| US-10287400-B2 | Curable silicone composition and applications and uses thereof | VCL, CCNI, SMCHD1 | TSHR 4542/4885KDM4E 2206/4885ALDH1A1 1443/4885 |
| US-12122730-B2 | Methods of carbon-carbon bond fragmentation | CYCS, COX6C, COXFA4L2 | TSHR 4604/4885KDM4E 4206/4885ALDH1A1 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.