Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323025 | 0.95 | L3MBTL1 (0.51) | KMT2AMAPK1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL3140840 | 0.83 | KMT2A (0.53) | KMT2AL3MBTL1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL13946703 | 0.83 | HRH3 (0.54) | KMT2AL3MBTL1RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL15242991 | 0.83 | L3MBTL1 (0.45) | KMT2AL3MBTL1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL632892 | 0.83 | L3MBTL1 (0.65) | KMT2AMAPK1L3MBTL1TSHRHRH3 | |
| SCHEMBL2132367 | 0.83 | L3MBTL1 (0.60) | KMT2AL3MBTL1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL917005 | 0.81 | L3MBTL1 (0.68) | KMT2AL3MBTL1RAB9ASMN1; SMN2SIGMAR1 | |
| SCHEMBL14199640 | 0.81 | ALDH1A1 (0.51) | KMT2AL3MBTL1SMN1; SMN2TSHRHRH3 | |
| SCHEMBL5872163 | 0.80 | L3MBTL1 (0.71) | L3MBTL1RAB9ASMN1; SMN2SIGMAR1HRH3 | |
| SCHEMBL4093054 | 0.80 | MCHR1 (0.51) | L3MBTL1RAB9ASMN1; SMN2HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114007-A1 | 5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-15 | — | — | US | disclosed |
| US-4247456-A | Water-insoluble monoazo pyridone dye | CASSELLA AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | disclosed |
| US-3957749-A | WATER-INSOLUBLE MONOAZO PYRIDINE DYES | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114007-A1 | 5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | FLT3, FES, ALK | KMT2A 2689/4885MAPK1 249/4885L3MBTL1 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.