SCHEMBL4894495

SCHEMBL4894495

[O]c1c2ccccc2nc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.56
ALDH1A1 P00352 5/20 0.56
GLA P06280 5/20 0.56
HPGD P15428 4/20 0.56
MAOA P21397 2/20 0.56
CASP1 P29466 2/20 0.56
CASP7 P55210 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
HSD17B10 Q99714 2/20 0.56
ACHE P22303 2/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
CHRM1 P11229 1/20 0.56
NQO2 P16083 1/20 0.56
DRD1 P21728 1/20 0.56
SLC6A2 P23975 1/20 0.56
ADRA1A P35348 1/20 0.56
OPRM1 P35372 1/20 0.56
KCNH2 Q12809 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7358788 0.77 PDE10A (0.59) KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL1502392 0.77 ALDH1A1 (0.62) KDM4EALDH1A1GLAHPGDMAOA
Anthraquinone SCHEMBL1376042 0.75 ALDH1A1 (0.41) KDM4EALDH1A1GLAHPGDMAOA
SCHEMBL13400206 0.74 ALDH1A1 (0.59) KDM4EALDH1A1GLAHPGDMAOA
SCHEMBL8061027 0.74 HSD17B10 (0.58) KDM4EALDH1A1GLAHPGDMAOA
SCHEMBL2360699 0.74 PLAUR (0.59) KDM4EALDH1A1GLAHPGDMAOA
SCHEMBL3042272 0.74 KDM4E (0.64) KDM4EALDH1A1GLAHPGDMAOA
SCHEMBL23172252 0.72 KDM4E (0.56) KDM4EALDH1A1GLAHPGDMAOA
SCHEMBL17423367 0.72 KDM4E (0.56) KDM4EALDH1A1GLAHPGDMAOA
SCHEMBL6842061 0.72 KDM4E (0.56) KDM4EALDH1A1GLAHPGDMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2491915-B1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO LTD (JP) 2019-07-03 EP disclosed
EP-2491915-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2012-08-29 EP disclosed
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2012-08-23 US disclosed
US-20080044149-A1 Polymerizable Composition TOYO INK MFG. CO., LTD. (JP) 2008-02-21 US disclosed
EP-1816152-A1 POLYMERIZABLE COMPOSITION TOYO INK MFG. CO., LTD. (JP) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SMARCA5, SMARCA1, SMARCA2 KDM4E 634/4885ALDH1A1 1369/4885GLA 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.