Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
| ▸ | GPR3 | P46089 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231530 | 0.80 | GPR3 (0.64) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL8061027 | 0.80 | HSD17B10 (0.58) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL28822932 | 0.78 | GPR3 (0.61) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27521191 | 0.78 | GPR3 (0.61) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL4894495 | 0.77 | KDM4E (0.56) | GPR3HSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL27296318 | 0.77 | ALDH1A1 (0.64) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL30025532 | 0.77 | ALDH1A1 (0.64) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL6788479 | 0.75 | GPR3 (0.57) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11985944 | 0.75 | GPR3 (0.57) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL6215008 | 0.75 | GPR3 (0.57) | PDE10AGPR3HSD17B10ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027332-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-08-16 | — | — | EP | disclosed |
| US-6057336-A | ANTIINFLAMMATORY AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| WO-1999018074-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Britol-Myers Squibb Pharma Company (US) | 1999-04-15 | — | — | WO | disclosed |