Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28110323 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL4524493 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL28110326 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL8221831 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL28417293 | 1.00 | LCK (0.48) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| Phosphine SCHEMBL10866020 | 0.97 | LCK (0.46) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL4533484 | 0.97 | LCK (0.44) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL12214087 | 0.94 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL5902659 | 0.94 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2TSHR | |
| SCHEMBL3095599 | 0.94 | LCK (0.52) | LCKPPARDZDHHC20ZDHHC2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111365-B | Perfluoro-substituted diamine, preparation method thereof and application thereof in preparation of polyimide film | 吉林大学 | 2020-04-24 | — | — | CN | disclosed |
| US-8822707-B2 | Nucleophile assisting leaving groups | FLORIDA ATLANTIC UNIVERSITY (US) | 2014-09-02 | — | — | US | disclosed |
| CN-100427567-C | Preparation method of multi-metal oxygen cluster organic/inorganic hybridization liquid crystal material | UNIV JILIN (CN) | 2008-10-22 | — | — | CN | disclosed |
| US-20080221347-A1 | Oligoether, crown ether linked to an acyclic or cyclic group linked with a sulfonate or silanol leaving group to an alkyl group, an alkenyl group, an alkynyl group or an optionally substituted aromatic or heteroaryl group; stabilized leaving group is more easily displaced | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-11 | — | — | US | disclosed |
| CN-1919970-A | Preparation method of multi-metal oxygen cluster organic/inorganic hybridization liquid crystal material | UNIV JILIN (CN) | 2007-02-28 | — | — | CN | disclosed |
| WO-2006060142-A2 | NUCLEOPHILE ASSISTING LEAVING GROUPS | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221347-A1 | Oligoether, crown ether linked to an acyclic or cyclic group linked with a sulfonate or silanol leaving group to an alkyl group, an alkenyl group, an alkynyl group or an optionally substituted aromatic or heteroaryl group; stabilized leaving group is more easily displaced | OSTC, STS, TST | LCK 1487/4885PPARD 3132/4885ZDHHC20 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.