Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | APC | P25054 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925996 | 0.94 | HPGD (0.49) | HPGDCDK5CDK5R1RIPK1ATR | |
| SCHEMBL2931324 | 0.85 | ATR (0.48) | HPGDCDK5CDK5R1RIPK1ATR | |
| SCHEMBL2927882 | 0.82 | RIPK1 (0.55) | HPGDCDK5CDK5R1RIPK1ATR | |
| Hydrochloric Acid SCHEMBL2935656 | 0.81 | RIPK1 (0.54) | HPGDCDK5CDK5R1RIPK1ATR | |
| SCHEMBL2930189 | 0.78 | ATR (0.52) | HPGDCDK5CDK5R1RIPK1ATR | |
| SCHEMBL13515285 | 0.77 | BTK (0.48) | HPGDCDK5CDK5R1RIPK1ATR | |
| Hydrochloric Acid SCHEMBL2933310 | 0.77 | BTK (0.48) | HPGDCDK5CDK5R1RIPK1ATR | |
| SCHEMBL16382911 | 0.73 | RIPK1 (0.58) | HPGDRIPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2936901 | 0.73 | FASN (0.53) | HPGDRIPK1JAK2HRH3 | |
| SCHEMBL2933173 | 0.72 | HPGD (0.50) | HPGDRIPK1ATRALDH1A1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039450-A1 | Compounds | BIOVITRUM AB (PUBL.) (SE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039450-A1 | Compounds | NEK2, CSNK2A3, CSNK2A1 | HPGD 3066/4885CDK5 240/4885CDK5R1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.