Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887223 | 0.84 | LMNA (0.40) | LMNAPTPN1ALDH1A1 | |
| SCHEMBL4898491 | 0.78 | LMNA (0.54) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL10454296 | 0.77 | LMNA (0.42) | LMNAPTPN1CYP2D6SPHK1GMNN | |
| SCHEMBL22418856 | 0.76 | LMNA (0.44) | LMNAPTPN1CYP2D6SPHK1GMNN | |
| SCHEMBL3645948 | 0.76 | LMNA (0.50) | LMNAPTPN1CYP2D6SPHK1GMNN | |
| SCHEMBL29023671 | 0.76 | LMNA (0.45) | LMNAPTPN1CYP2D6SPHK1GMNN | |
| SCHEMBL4891055 | 0.76 | LMNA (0.56) | LMNA | |
| SCHEMBL4893444 | 0.76 | LMNA (0.50) | LMNA | |
| SCHEMBL3630693 | 0.75 | PTPN1 (0.39) | LMNAPTPN1CYP2D6SPHK1GMNN | |
| SCHEMBL4881453 | 0.75 | ALDH1A1 (0.42) | LMNAPTPN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293880-A1 | Liquid, Thermally Curable Mixtures, Their Preparation and Use | BASF COATINGS AG (DE) | 2008-11-27 | — | — | US | claimed |