Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | NPY1R | P25929 | 1/20 | 0.65 |
| ▸ | NPY2R | P49146 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4903392 | 0.99 | ADRB2 (0.65) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL11037618 | 0.86 | ADRB2 (0.62) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL9354060 | 0.84 | ADRB2 (0.79) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL9628892 | 0.84 | ADRB2 (0.78) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL10072155 | 0.84 | ADRB2 (0.78) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL6674480 | 0.84 | ADRB2 (0.78) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Hydrochloric Acid SCHEMBL11205198 | 0.83 | TDP1 (0.59) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Hydrochloric Acid SCHEMBL1269430 | 0.83 | ADRB2 (0.77) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Hydrochloric Acid SCHEMBL6016823 | 0.83 | ADRB2 (0.76) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL13575765 | 0.82 | ADRB2 (0.67) | ADRB2ADRB1TDP1LMNAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041491-B1 | NEW PARA-SUBSTITUTED 3-PHENOXY-1-ALKYLAMINO-PROPANOL-2-S HAVING BETA RECEPTOR BLOCKING PROPERTIES | Aktiebolaget Hässle (SE) | 1985-01-30 | — | — | EP | claimed |
| EP-2948379-A1 | READY-TO-USE CO-SOLVENTS PHARMACEUTICAL COMPOSITION IN MODIFIED FLEXIBLE PLASTIC CONTAINER | HQ Specialty Pharma Corporation (US) | 2015-12-02 | — | — | EP | disclosed |
| US-20140364503-A1 | READY-TO-USE CO-SOLVENTS PHARMACEUTICAL COMPOSITION IN MODIFIED FLEXIBLE PLASTIC CONTAINER | Welgrace Research Group (US) | 2014-12-11 | — | — | US | disclosed |
| WO-2014143845-A1 | READY-TO-USE CO-SOLVENTS PHARMACEUTICAL COMPOSITION IN MODIFIED FLEXIBLE PLASTIC CONTAINER | Welgrace Research Group (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20140262915-A1 | READY-TO-USE CO-SOLVENTS PHARMACEUTICAL COMPOSITION IN MODIFIED FLEXIBLE PLASTIC CONTAINER | HQ Specialty Pharma Corporation (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275249-A1 | READY-TO-USE CO-SOLVENTS PHARMACEUTICAL COMPOSITION IN MODIFIED FLEXIBLE PLASTIC CONTAINER | HQ Specialty Pharma Corporation (US) | 2014-09-18 | — | — | US | disclosed |
| US-8835505-B1 | Ready-to-use co-solvents pharmaceutical composition in modified flexible plastic container | Welgrace Research Group (US) | 2014-09-16 | — | — | US | disclosed |
| US-8829054-B1 | Ready-to-use co-solvents pharmaceutical composition in modified flexible plastic container | Welgrace Research Group (US) | 2014-09-09 | — | — | US | disclosed |
| US-8722736-B2 | Multi-dose concentrate esmolol with benzyl alcohol | BAXTER INTERNATIONAL INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20080293810-A1 | MULTI-DOSE CONCENTRATE ESMOLOL WITH BENZYL ALCOHOL | BAXTER HEALTHCARE S.A. (CH) | 2008-11-27 | — | — | US | disclosed |
| US-4080471-A | ANTIARRYTHMIA | AKTIEBOLAGET HASSLE (SW) | 1978-03-21 | — | — | US | disclosed |