Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | CNR1 | P21554 | 1/20 | 0.78 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.78 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
| ▸ | THPO | P40225 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628892 | 1.00 | ADRB2 (0.78) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL6674480 | 1.00 | ADRB2 (0.78) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Hydrochloric Acid SCHEMBL6016823 | 0.99 | ADRB2 (0.76) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL10961494 | 0.89 | ADRB2 (0.78) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Atenolol SCHEMBL18120 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL10737751 | 0.88 | ADRB2 (0.76) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Atenolol SCHEMBL4362 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1TDP1LMNAPMP22 | |
| SCHEMBL6016784 | 0.88 | ADRB2 (0.77) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Atenolol SCHEMBL6509830 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1TDP1LMNAPMP22 | |
| Esatenolol SCHEMBL4363 | 0.88 | ADRB2 (1.00) | ADRB2ADRB1TDP1LMNAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045505-A1 | FIXED DOSE DRUG COMBINATION FORMULATIONS | DR. REDDY'S LABORATORIES, INC. (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045505-A1 | FIXED DOSE DRUG COMBINATION FORMULATIONS | SLC5A6, TNNT2, SIRT6 | ADRB2 259/4885ADRB1 214/4885TDP1 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.