Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31117941 | 0.88 | RECQL (0.50) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL15085735 | 0.87 | HPGD (0.57) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL25723161 | 0.85 | HPGD (0.55) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL31622247 | 0.85 | RECQL (0.54) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL31496250 | 0.83 | HPGD (0.50) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL23539626 | 0.83 | RECQL (0.43) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL23541130 | 0.83 | RECQL (0.43) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL4041166 | 0.81 | HPGD (0.51) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL27145278 | 0.79 | GPR119 (0.48) | RECQLHPGDUSP2SMN1; SMN2KDM4E | |
| SCHEMBL12082 | 0.79 | HPGD (0.55) | RECQLHPGDUSP2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312281-A1 | G-Protein Coupled Receptor (Gpr116) Agonists and Use Thereof for Treating Obesity and Diabetes | PROSIDION LIMITED (GB) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312281-A1 | G-Protein Coupled Receptor (Gpr116) Agonists and Use Thereof for Treating Obesity and Diabetes | GPR119, GCGR, GPR65 | RECQL 4343/4885HPGD 1537/4885USP2 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.