SCHEMBL48954

SCHEMBL48954

CC(C)(O[SiH3])c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.64
ALDH1A1 P00352 3/20 0.58
ALOX15 P16050 1/20 0.58
TAAR1 Q96RJ0 1/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
CYP3A4 P08684 1/20 0.39
KCNN4 O15554 4/20 0.39
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.38
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP2B6 P20813 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6287535 0.81 MAPK1 (0.44) MAPK1ALDH1A1ALOX15TAAR1CYP3A4
SCHEMBL675685 0.79 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL3340231 0.78 MAOB (0.44) MAPK1ALDH1A1ALOX15CYP3A4MAPT
Benzene SCHEMBL25312146 0.78 MAPK1 (1.00) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL27506519 0.78 MAPK1 (1.00) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL960581 0.78 MAPK1 (0.70) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL8939342 0.78 MAPK1 (1.00) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL15450 0.78 MAPK1 (1.00) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL3482427 0.77 TSHR (0.52) MAPK1ALDH1A1ALOX15CYP3A4MAPT
Hydrogen Peroxide SCHEMBL22163808 0.76 MAPK1 (0.94) MAPK1ALDH1A1ALOX15TAAR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 978 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634324-A1 AMPHIPHILIC ABRASIVE PARTICLES AND THEIR USE FOR CHEMICAL MECHANICAL PLANARIZATION Versum Materials US, LLC (US) 2025-10-22 EP claimed
CN-119431794-A Organosilicon tackifier and preparation method and application thereof 杭州之江有机硅化工有限公司 2025-02-14 CN claimed
CN-119100394-A Method for preparing high-purity nano silicon carbide powder by combining microwave heating technology with self-suspension carbothermal reduction technology 绍兴晶彩科技有限公司 2024-12-10 CN claimed
US-20240309144-A1 SILANE MODIFIED ALIPHATIC POLYUREA EVONIK OPERATIONS GMBH (DE) 2024-09-19 US claimed
WO-2024129435-A1 AMPHIPHILIC ABRASIVE PARTICLES AND THEIR USE FOR CHEMICAL MECHANICAL PLANARIZATION VERSUM MATERIALS US, LLC (US) 2024-06-20 WO claimed
EP-4370573-A1 SILANE MODIFIED ALIPHATIC POLYUREA Evonik Operations GmbH (DE) 2024-05-22 EP claimed
CN-117866205-A Silicon-containing surface modifier and resist underlayer film composition, and preparation method and application thereof 福建泓光半导体材料有限公司 2024-04-12 CN claimed
CN-117327281-A Core-shell type organic silicon resin and ink prepared from same for packaging flexible OLED display thin film 江苏广信感光新材料股份有限公司 2024-01-02 CN claimed
CN-117203256-A Silane-modified aliphatic polyureas 赢创运营有限公司 2023-12-08 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
EP-1769512-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS Dow Corning Corporation (US) 2007-04-04 EP claimed
WO-2006121644-A1 OPTICAL INFORMATION STORAGE MEDIUM POSSESSING A MULTILAYER COATING GENERAL ELECTRIC COMPANY (US) 2006-11-16 WO claimed
US-20060251848-A1 Optical information storage medium possessing a multilayer coating MOMENTIVE PERFORMANCE MATERIALS INC. 2006-11-09 US claimed
US-20060251906-A1 Curable composition and article possessing protective layer obtained therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-11-09 US claimed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO claimed
US-6697712-B1 Distributed cable feed system and method UTILX CORPORATION 2004-02-24 US claimed
EP-0457175-B1 Method of purification of alkoxysilanes TOSHIBA SILICONE (JP) 1997-02-12 EP claimed
EP-0278157-B1 A RUBBER COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 1993-06-16 EP claimed
US-5104999-A METHOD OF PURIFICATION OF ALKOXYSILANES TOSHIBA SILICONE CO., LTD. (JP) 1992-04-14 US claimed
EP-0457175-A2 Method of purification of alkoxysilanes TOSHIBA SILICONE CO., LTD. (JP) 1991-11-21 EP claimed