SCHEMBL6287535

SCHEMBL6287535

CC(C)(O[SiH3])c1ccccc1.[SiH3]OCC(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 1/20 0.41
ALOX15 P16050 1/20 0.41
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
HRH1 P35367 4/20 0.35
SLC6A3 Q01959 2/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CACNA1F O60840 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
ADRA2B P18089 1/20 0.35
CHRM3 P20309 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRK1 P41145 1/20 0.35
CACNA1D Q01668 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48954 0.81 MAPK1 (0.64) MAPK1ALDH1A1ALOX15TAAR1CYP3A4
SCHEMBL675686 0.81 CA12 (0.47) HRH1CA12CA1CA2CA9
SCHEMBL1313820 0.71 RIPK1 (0.37) HRH1SLC6A3CACNA1FCHRM2CHRM1
SCHEMBL28793286 0.69 MAPK1 (0.39) MAPK1ALDH1A1ALOX15RIPK1TAAR1
SCHEMBL18662228 0.68 HTR2A (0.38) MAPK1CNR1CNR2HRH1SLC6A3
SCHEMBL707821 0.68 HRH1 (0.40) HRH1SLC6A3CACNA1FCHRM2CHRM1
SCHEMBL4360668 0.68 RIPK1 (0.47) MAPK1ALDH1A1ALOX15HRH1SLC6A3
SCHEMBL6287521 0.68 CA12 (0.34) HRH1CA12CA1CA2CA9
SCHEMBL6268405 0.67 TAAR1 (0.52) ALDH1A1RIPK1TAAR1TACR1KDM4E
SCHEMBL3809923 0.66 CA12 (0.41) HRH1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852368-B2 Hard coating composition and resin product with hard coat NIPPON ARC CO., LTD. (JP) 2005-02-08 US disclosed
US-20030194571-A1 Hard coating composition and resin product with hard coat NIPPON ARC CO., LTD. (JP) 2003-10-16 US disclosed
EP-1298177-A1 HARD COATING COMPOSITION AND RESIN PRODUCT WITH HARD COAT NIPPON ARC CO., LTD. (JP) 2003-04-02 EP disclosed