Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4896665 | 0.96 | NPC1 (0.36) | AKR1C3TYK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4903017 | 0.88 | F10 (0.40) | F10AKR1C3TYK2HPGDSHTR6 | |
| SCHEMBL4899219 | 0.88 | F10 (0.35) | F10AKR1C3TYK2HPGDSPIM1 | |
| SCHEMBL5262033 | 0.88 | F10 (0.35) | F10AKR1C3TYK2SMN1; SMN2HPGDS | |
| Hydrochloric Acid SCHEMBL4896752 | 0.87 | F10 (0.35) | F10AKR1C3TYK2SMN1; SMN2HPGDS | |
| SCHEMBL4900748 | 0.85 | F10 (0.37) | F10AKR1C3TYK2HPGDSGAA | |
| SCHEMBL4891094 | 0.85 | AKR1C3 (0.35) | AKR1C3TYK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4902865 | 0.85 | AKR1C3 (0.35) | AKR1C3TYK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4899105 | 0.84 | CCNA2 (0.46) | TYK2CDK2CCNA2 | |
| Hydrochloric Acid SCHEMBL5312344 | 0.84 | F10 (0.36) | F10AKR1C3TYK2HPGDSGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | F10 1686/4885AKR1C3 1318/4885TYK2 2831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.