Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900748 | 0.97 | F10 (0.37) | F10LMNAHPGDTSHRAKR1C3 | |
| Hydrochloric Acid SCHEMBL5312344 | 0.96 | F10 (0.36) | F10LMNAHPGDTSHRAKR1C3 | |
| SCHEMBL4895704 | 0.88 | F10 (0.36) | F10AKR1C3HPGDSHTR6FFAR1 | |
| SCHEMBL5262033 | 0.86 | F10 (0.35) | F10LMNAHPGDTSHRAKR1C3 | |
| SCHEMBL4899219 | 0.86 | F10 (0.35) | F10AKR1C3HPGDSCDK4CCND1 | |
| Hydrochloric Acid SCHEMBL4896752 | 0.85 | F10 (0.35) | F10LMNAHPGDTSHRAKR1C3 | |
| SCHEMBL4892130 | 0.84 | CCNA2 (0.44) | CCNT1CDK4CCND1CDK9CDK6 | |
| SCHEMBL4901325 | 0.84 | PIP4K2A (0.38) | F10HPGDAKR1C3HPGDSCCNT1 | |
| Hydrochloric Acid SCHEMBL4896665 | 0.84 | NPC1 (0.36) | LMNAHPGDAKR1C3HPGDSMAPK8 | |
| Hydrochloric Acid SCHEMBL5315908 | 0.84 | CDK6 (0.40) | CCNT1CDK4CCND1CDK9CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | F10 1686/4885LMNA 3338/4885HPGD 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.