Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4896752 | 0.99 | F10 (0.35) | F10AKR1C3USP2TYK2LMNA | |
| SCHEMBL4891094 | 0.97 | AKR1C3 (0.35) | AKR1C3USP2TYK2LMNAMAPT | |
| SCHEMBL4895704 | 0.88 | F10 (0.36) | F10AKR1C3TYK2PIM1PIM3 | |
| SCHEMBL4903017 | 0.86 | F10 (0.40) | F10AKR1C3TYK2LMNAHPGD | |
| SCHEMBL4899219 | 0.85 | F10 (0.35) | F10AKR1C3TYK2PIM1PIM3 | |
| SCHEMBL27662832 | 0.84 | CCNA2 (0.41) | TYK2LYNSRC | |
| Hydrochloric Acid SCHEMBL4904855 | 0.84 | CCNA2 (0.39) | TYK2LYNSRC | |
| Hydrochloric Acid SCHEMBL4896665 | 0.84 | NPC1 (0.36) | AKR1C3TYK2LMNASRCHPGD | |
| Hydrochloric Acid SCHEMBL4899525 | 0.84 | CCNA2 (0.41) | TYK2LYNSRC | |
| SCHEMBL4900748 | 0.83 | F10 (0.37) | F10AKR1C3TYK2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737852-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100349-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2005-10-27 | — | — | WO | disclosed |