Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331750 | 0.80 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL1284120 | 0.77 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL137371 | 0.75 | TSHR (0.61) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL13863117 | 0.75 | TSHR (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL3627742 | 0.75 | TSHR (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL17805317 | 0.75 | TSHR (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL9301462 | 0.74 | TSHR (0.56) | TSHRTHRBALDH1A1 | |
| SCHEMBL13863105 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1 | |
| SCHEMBL235662 | 0.74 | TSHR (0.47) | TSHRTHRBALDH1A1 | |
| SCHEMBL35710 | 0.73 | TSHR (0.50) | TSHRTHRBALDH1A1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015282-A1 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS | JOHNSON & JOHNSON VISION CARE, INC. | 2008-01-17 | — | — | US | claimed |