Diclofop

Diclofop

SCHEMBL4895804

C[C@@H](Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.62
TSHR P16473 1/20 0.58
HTR2A P28223 1/20 0.58
HTR2C P28335 1/20 0.58
HTR2B P41595 1/20 0.58
MRGPRX4 Q96LA9 1/20 0.51
TTR P02766 1/20 0.50
PTGDR2 Q9Y5Y4 2/20 0.49
PTGDR Q13258 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
GAA P10253 1/20 0.49
PKM P14618 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
HTT P42858 1/20 0.48
MAP4K4 O95819 2/20 0.47
GLA P06280 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diclofop SCHEMBL66474 1.00 FFAR1 (0.62) FFAR1TSHRHTR2AHTR2CHTR2B
Diclofop SCHEMBL30583165 1.00 FFAR1 (0.62) FFAR1TSHRHTR2AHTR2CHTR2B
Diclofop SCHEMBL1011415 1.00 FFAR1 (0.62) FFAR1TSHRHTR2AHTR2CHTR2B
Diclofop SCHEMBL10965623 0.96 FFAR1 (0.58) FFAR1TSHRHTR2AHTR2CHTR2B
Diclofop SCHEMBL11436235 0.95 FFAR1 (0.60) FFAR1TSHRHTR2AHTR2CHTR2B
Diclofop-Methyl SCHEMBL8541475 0.92 FFAR1 (0.55) FFAR1TSHRHTR2AHTR2CHTR2B
Diclofop-Methyl SCHEMBL7751604 0.90 FFAR1 (0.53) FFAR1TSHRHTR2AHTR2CHTR2B
Diclofop SCHEMBL11459120 0.89 PPARA (0.53) FFAR1TSHRHTR2AHTR2CHTR2B
SCHEMBL10430655 0.89 FFAR1 (0.59) FFAR1TSHRHTR2AHTR2CHTR2B
SCHEMBL11442195 0.89 TSHR (0.55) FFAR1TSHRHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11299745-B1 Herbicide resistance genes DOW AGROSCIENCES LLC (US) 2022-04-12 US claimed
US-20220098610-A1 NOVEL HERBICIDE RESISTANCE GENES DOW AGROSCIENCES LLC (US) 2022-03-31 US claimed
EP-0273668-B1 HERBICIDAL METHOD USING DIFLUFENICAN MAY & BAKER LIMITED (GB) 1992-07-01 EP claimed
EP-0255272-B1 HERBICIDAL METHOD COMPRISING THE USE OF DIFLUFENICAN MAY & BAKER LIMITED (GB) 1991-12-11 EP claimed
US-4940484-A Herbicidal method comprising the use of diflufenican MAY AND BAKER LIMITED (GB) 1990-07-10 US claimed
US-4935508-A Acylation of 7-aminocephalosporin with alkyl 2-(2-amino-thiazol-4-yl)-2-oximinoacetate BRISTOL-MYERS COMPANY (US) 1990-06-19 US claimed
EP-0255272-A1 Herbicidal method comprising the use of diflufenican MAY & BAKER LIMITED (GB) 1988-02-03 EP claimed
US-9961900-B2 Herbicide formulations VIVE CROP PROTECTION INC. (CA) 2018-05-08 US disclosed
US-20150141249-A1 HERBICIDE FORMULATIONS VIVE CORP PROTECTION INC. (CA) 2015-05-21 US disclosed
WO-2013186695-A1 HERBICIDE FORMULATIONS VIVE CROP PROTECTION INC. (CA) 2013-12-19 WO disclosed
US-20080269052-A1 USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS BAYER CROPSCIENCE AG (DE) 2008-10-30 US disclosed
EP-0273668-B1 HERBICIDAL METHOD USING DIFLUFENICAN MAY & BAKER LIMITED (GB) 1992-07-01 EP disclosed
US-5110943-A Herbicides SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1992-05-05 US disclosed
EP-0255272-B1 HERBICIDAL METHOD COMPRISING THE USE OF DIFLUFENICAN MAY & BAKER LIMITED (GB) 1991-12-11 EP disclosed
US-5037759-A Oxidation of substituted phenoxy propane by bacteria SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1991-08-06 US disclosed
US-4940484-A Herbicidal method comprising the use of diflufenican MAY AND BAKER LIMITED (GB) 1990-07-10 US disclosed
US-4940484-A Herbicidal method comprising the use of diflufenican MAY AND BAKER LIMITED (GB) 1990-07-10 US disclosed
EP-0319100-A2 Process for the preparation of substituted phenoxy propanoic acids SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-06-07 EP disclosed
US-4803301-A Process for producing optically active 2-phenoxypropionic acid KIRIN BEER KABUSHIKI KAISHA (JP) 1989-02-07 US disclosed
EP-0255272-A1 Herbicidal method comprising the use of diflufenican MAY & BAKER LIMITED (GB) 1988-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269052-A1 USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS CBR3, CBR1, CYP4Z1 FFAR1 1478/4885TSHR 1304/4885HTR2A 1119/4885
US-20150141249-A1 HERBICIDE FORMULATIONS DDT, PGAM5, PNPO FFAR1 1692/4885TSHR 4142/4885HTR2A 2791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.