⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903068 | 0.87 | CXCR2 (0.31) | — | |
| SCHEMBL4902465 | 0.84 | KCNH2 (0.33) | — | |
| SCHEMBL4896688 | 0.83 | — | — | |
| SCHEMBL4900372 | 0.83 | PDE2A (0.32) | — | |
| SCHEMBL4902690 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL4875986 | 0.79 | KCNH2 (0.36) | — | |
| SCHEMBL4877771 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL4892355 | 0.72 | PKM (0.34) | — | |
| SCHEMBL4900356 | 0.72 | FASN (0.32) | — | |
| SCHEMBL4903195 | 0.70 | FASN (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | PFIZER INC. (US) | 2008-06-05 | — | — | US | claimed |
| US-20080132549-A1 | Sulphur-Linked Imidazone Compounds for the Treatment of Hiv/Aids | PFIZER INC. (US) | 2008-06-05 | — | — | US | disclosed |
| EP-1740550-A1 | SULPHUR-LINKED IMIDAZOLE COMPOUNDS FOR THE TREAMENT OF HIV | Pfizer Limited (GB) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100322-A1 | SULPHUR-LINKED IMIDAZOLE COMPOUNDS FOR THE TREAMENT OF HIV | PFIZER LIMITED (GB) | 2005-10-27 | — | — | WO | disclosed |