Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.66 |
| ▸ | CA9 | Q16790 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330654 | 0.87 | CA2 (0.69) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL7498033 | 0.86 | CA2 (0.83) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8273562 | 0.86 | POLB (0.72) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| Sulfanitran SCHEMBL93837 | 0.85 | KMT2A (1.00) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL23093556 | 0.85 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL14288331 | 0.84 | HDAC1 (0.64) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL23093376 | 0.83 | KDM1A (0.62) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL5315455 | 0.83 | HDAC3 (0.73) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6577363 | 0.81 | CA2 (0.71) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL12338982 | 0.81 | MAPT (1.00) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059658-A1 | QUINOLINE DERIVATIVES AND USES IN MANAGING CANCER | UNIV EMORY (US) | 2024-02-22 | — | — | US | disclosed |
| WO-2021050721-A1 | QUINOLINE DERIVATIVES AND USES IN MANAGING CANCER | EMORY UNIVERSITY (US) | 2021-03-18 | — | — | WO | disclosed |
| US-20080293970-A1 | Process for Synthesis of 4-4'-Diamino-Diphenyl-Sulfone | LUNDBECK PHARMACEUTICALS ITALY S.P.A. | 2008-11-27 | — | — | US | disclosed |
| EP-1778630-A1 | PROCESS FOR SYNTHESIS OF 4-4'-DIAMINO-DIPHENYL-SULFONE | Lundbeck Pharmaceuticals Italy S.P.A. (IT) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006002690-A1 | PROCESS FOR SYNTHESIS OF 4-4'-DIAMINO-DIPHENYL-SULFONE | LUNDBECK PHARMACEUTICALS ITALY S.P.A. (IT) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059658-A1 | QUINOLINE DERIVATIVES AND USES IN MANAGING CANCER | MDM2, TP53, RECQL | MEN1 1224/4885KMT2A 651/4885ALDH1A1 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.