Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891951 | 0.92 | HDAC3 (0.66) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL3812243 | 0.88 | HDAC1 (0.64) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL1521002 | 0.88 | RAB9A (0.71) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL4895996 | 0.85 | HDAC3 (0.58) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL3812238 | 0.84 | HDAC1 (0.59) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL8348849 | 0.81 | HDAC1 (0.60) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL7789440 | 0.79 | HDAC1 (0.79) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL21963302 | 0.78 | LMNA (0.59) | HDAC1HDAC3NPC1RAB9A | |
| SCHEMBL674310 | 0.77 | HDAC1 (0.75) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL2107762 | 0.77 | HDAC1 (0.65) | HDAC1HDAC3HDAC2HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234254-A1 | Inhibitors of Histone Deacetylase | UNIVERSITY OF LEEDS (GB) | 2008-09-25 | — | — | US | disclosed |
| EP-1758847-A1 | INHIBITORS OF HISTONE DEACETYLASE | Cancer Research Technology Limited (GB) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121073-A1 | INHIBITORS OF HISTONE DEACETYLASE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234254-A1 | Inhibitors of Histone Deacetylase | HDAC8, HDAC4, HDAC5 | HDAC1 4/4885HDAC3 5/4885HDAC2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.