Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189634 | 0.87 | FAAH (0.78) | FAAH | |
| SCHEMBL4173180 | 0.81 | FAAH (0.77) | FAAH | |
| SCHEMBL12420272 | 0.77 | FAAH (0.78) | FAAH | |
| SCHEMBL4190828 | 0.74 | FAAH (0.74) | FAAH | |
| SCHEMBL4187377 | 0.74 | FAAH (0.76) | FAAH | |
| SCHEMBL4189660 | 0.74 | FAAH (0.77) | FAAH | |
| SCHEMBL4190723 | 0.74 | FAAH (1.00) | FAAH | |
| SCHEMBL4187016 | 0.74 | FAAH (1.00) | FAAH | |
| SCHEMBL4177803 | 0.74 | FAAH (1.00) | FAAH | |
| SCHEMBL4180650 | 0.73 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954137-A4 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1954137-A2 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007061862-A2 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-31 | — | — | WO | disclosed |