SCHEMBL489662

SCHEMBL489662

CCCCCCCC/C=C\CCCCCCCCO[Si](C)(OCCCCCCCC/C=C\CCCCCCCC)OCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.50
LPAR3 Q9UBY5 3/20 0.50
LPAR1 Q92633 2/20 0.50
FAAH O00519 2/20 0.48
TRPV1 Q8NER1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL489663 1.00 LPAR2 (0.50) LPAR2LPAR3LPAR1FAAHTRPV1
SCHEMBL5701269 0.88 LPAR2 (0.50) LPAR2LPAR3LPAR1FAAHTRPV1
SCHEMBL5701279 0.88 LPAR2 (0.50) LPAR2LPAR3LPAR1FAAHTRPV1
SCHEMBL5701264 0.88 LPAR2 (0.50) LPAR2LPAR3LPAR1FAAHTRPV1
SCHEMBL5701277 0.88 LPAR2 (0.50) LPAR2LPAR3LPAR1FAAHTRPV1
SCHEMBL661840 0.87 THRB (0.44) LPAR2LPAR3LPAR1
SCHEMBL7786537 0.87 THRB (0.44) LPAR2LPAR3LPAR1
SCHEMBL7568440 0.87 THRB (0.44) LPAR2LPAR3LPAR1
SCHEMBL662567 0.87 THRB (0.44) LPAR2LPAR3LPAR1
SCHEMBL661550 0.87 THRB (0.44) LPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1914264-B1 SURFACE-TREATED POWDER AND COSMETIC COMPRISING THE SAME MIYOSHI KASEI INC (JP) 2018-08-29 EP disclosed
US-8105691-B2 Hydrophilized surface-treated powder and cosmetics containing same MIYOSHI KASEI, INC. (JP) 2012-01-31 US disclosed
US-7682622-B2 Cosmetics MIYOSHI KASEI, INC. (JP) 2010-03-23 US disclosed
US-20090263660-A1 SURFACE-TREATED POWDER AND COSMETICS CONTAINING SAME MIYOSHI KASEI, INC. (JP) 2009-10-22 US disclosed
EP-1914264-A1 SURFACE-TREATED POWDER AND COSMETIC COMPRISING THE SAME Miyoshi Kasei, Inc. (JP) 2008-04-23 EP disclosed
US-20050196363-A1 Cosmetics MIYOSHI KASEI, INC. (JP) 2005-09-08 US disclosed
US-20050169867-A1 Cosmetics MIYOSHI KASEI, INC. (JP) 2005-08-04 US disclosed