SCHEMBL4896716

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4745429	0.91	HDAC6 (0.50)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL4744989	0.83	HDAC6 (0.59)	HDAC3HDAC1HDAC2NCOR2HDAC8
	SCHEMBL14025812	0.76	PKM (0.47)	HDAC3HDAC1HDAC8HDAC6TAS2R14
	SCHEMBL4888218	0.75	HDAC3 (0.56)	HDAC3HDAC1HDAC2NCOR2HDAC8
	SCHEMBL17675324	0.73	SYK (0.50)	HDAC3HDAC1HDAC2HDAC8HDAC6
	SCHEMBL4749020	0.72	HDAC6 (0.66)	HDAC3HDAC1HDAC2NCOR2HDAC8
	SCHEMBL14025742	0.71	NAMPT (0.52)	SYKPKM
	SCHEMBL1861286	0.71	GAA (0.55)	TAS2R14GAA
	SCHEMBL14005231	0.70	HDAC6 (0.61)	HDAC3HDAC1HDAC2NCOR2HDAC8
	SCHEMBL13879819	0.70	PKM (0.52)	HDAC1HDAC8HDAC6SYKPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.