SCHEMBL4896934

SCHEMBL4896934

O=C(O)c1c2ccccc2cc2cc3ccccc3cc12

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.84
MEN1 O00255 3/20 0.84
KMT2A Q03164 3/20 0.84
KDM4E B2RXH2 2/20 0.84
HSD17B10 Q99714 2/20 0.84
CYP1A2 P05177 2/20 0.84
GLA P06280 1/20 0.84
HPGD P15428 1/20 0.84
CYP2C19 P33261 1/20 0.84
GAA P10253 1/20 0.47
ME2 P23368 1/20 0.45
ME1 P48163 1/20 0.45
ME3 Q16798 1/20 0.45
CDC25B P30305 3/20 0.45
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31125071 0.92 KDM4E (0.69) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL122832 0.92 MEN1 (1.00) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL29352186 0.92 MEN1 (1.00) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL28099540 0.90 MEN1 (0.95) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL27733356 0.90 MEN1 (0.95) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL28121546 0.90 MEN1 (0.95) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL7054301 0.90 MEN1 (0.95) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL11788252 0.90 MEN1 (0.95) ALDH1A1MEN1KMT2AKDM4EHSD17B10
Anthracene-9-Carboxylic Acid SCHEMBL28243282 0.88 MEN1 (0.91) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL4896927 0.84 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111303860-B Long-afterglow luminescent material based on quantum dot sensitization and application thereof 复旦大学 2021-05-14 CN claimed
CN-111303860-A Long-afterglow luminescent material based on quantum dot sensitization and application thereof 复旦大学 2020-06-19 CN claimed
CN-109862890-A Purifying CENICRIVIROC and the purifying intermediate for being used to prepare CENICRIVIROC 妥必徕疗治公司 2019-06-07 CN claimed
CN-113412261-A Benzimidazole compounds, preparation method and use thereof 四川科伦博泰生物医药股份有限公司 2021-09-17 CN disclosed
CN-111303860-B Long-afterglow luminescent material based on quantum dot sensitization and application thereof 复旦大学 2021-05-14 CN disclosed
CN-111303860-A Long-afterglow luminescent material based on quantum dot sensitization and application thereof 复旦大学 2020-06-19 CN disclosed
US-10351580-B2 Acene-based transmitter molecules for photon upconversion THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-07-16 US disclosed
EP-2491915-B1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO LTD (JP) 2019-07-03 EP disclosed
CN-109862890-A Purifying CENICRIVIROC and the purifying intermediate for being used to prepare CENICRIVIROC 妥必徕疗治公司 2019-06-07 CN disclosed
EP-2491915-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2012-08-29 EP disclosed
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2012-08-23 US disclosed
US-20080044149-A1 Polymerizable Composition TOYO INK MFG. CO., LTD. (JP) 2008-02-21 US disclosed
EP-1816152-A1 POLYMERIZABLE COMPOSITION TOYO INK MFG. CO., LTD. (JP) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351580-B2 Acene-based transmitter molecules for photon upconversion ACE, ACE2, AGTR1 ALDH1A1 93/4885MEN1 1290/4885KMT2A 4292/4885
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SMARCA5, SMARCA1, SMARCA2 ALDH1A1 1369/4885MEN1 2816/4885KMT2A 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.