SCHEMBL4896937

SCHEMBL4896937

CCCCCC(NC(=N)N)NC(=N)N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 3/20 0.41
SPHK2 Q9NRA0 1/20 0.41
CNR2 P34972 2/20 0.41
OPRM1 P35372 1/20 0.39
LMNA P02545 2/20 0.37
TP53 P04637 2/20 0.36
LAP3 P28838 2/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
CYP2D6 P10635 2/20 0.35
GMNN O75496 1/20 0.35
POLB P06746 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
BLM P54132 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28977889 0.98 SPHK1 (0.45) SPHK1SPHK2CNR2OPRM1LMNA
SCHEMBL4536662 0.98 SPHK1 (0.45) SPHK1SPHK2CNR2OPRM1LMNA
Hydrochloric Acid SCHEMBL3722897 0.96 SPHK1 (0.43) SPHK1SPHK2CNR2OPRM1LMNA
SCHEMBL6380455 0.90 SPHK1 (0.42) SPHK1SPHK2CNR2OPRM1LMNA
Acetic Acid SCHEMBL11113366 0.89 CNR2 (0.45) CNR2MAPTGPR84
Nitric Acid SCHEMBL11104083 0.88 CNR2 (0.38) SPHK1SPHK2CNR2OPRM1TP53
Lactic Acid SCHEMBL11109148 0.86 GPR84 (0.44) CNR2MAPTGPR84
Acetic Acid SCHEMBL1123274 0.82 GPR84 (0.42) CNR2MAPTGPR84
Hydrochloric Acid SCHEMBL11114658 0.82 NOS3 (0.31) SPHK1SPHK2NOS3NOS1NOS2
SCHEMBL21908450 0.81 PLA2G2C (0.42) SPHK1SPHK2OPRM1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3817730-A1 COMPOSITIONS AND METHODS OF TREATMENT Blueberry Therapeutics Limited (GB) 2021-05-12 EP disclosed
EP-3817729-A1 COMPOSITIONS AND METHODS OF TREATMENT Blueberry Therapeutics Limited (GB) 2021-05-12 EP disclosed
WO-2020008196-A1 COMPOSITIONS AND METHODS OF TREATMENT BLUEBERRY THERAPEUTICS LIMITED (GB) 2020-01-09 WO disclosed
WO-2020008195-A1 COMPOSITIONS AND METHODS OF TREATMENT BLUEBERRY THERAPEUTICS LIMITED (GB) 2020-01-09 WO disclosed
WO-2019175873-A1 COMPOUNDS AND USES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGRAVATED BY IMPARED MITOPHAGY YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2019-09-19 WO disclosed
EP-3432867-A1 COMPOSITION AND METHODS OF TREATMENT Blueberry Therapeutics Limited (GB) 2019-01-30 EP disclosed
EP-3319640-A1 COMPOSITION AND METHODS OF TREATMENT Blueberry Therapeutics Limited (GB) 2018-05-16 EP disclosed
WO-2017163091-A1 COMPOSITION AND METHODS OF TREATMENT BLUEBERRY THERAPEUTICS LIMITED (GB) 2017-09-28 WO disclosed
WO-2017006112-A1 COMPOSITION AND METHODS OF TREATMENT BLUEBERRY THERAPEUTICS LIMITED (GB) 2017-01-12 WO disclosed
EP-3049056-A1 ANTIFUNGAL TOPICAL COMPOSITION AND METHODS OF TREATMENT Blueberry Therapeutics Limited (GB) 2016-08-03 EP disclosed
CN-101148452-A Oral cavity articles, preparation method and application thereof HAOWEI CO LTD (VG) 2008-03-26 CN disclosed
CN-101148451-A Oral cavity medicament and oral cavity nursing article HAOWEI CO LTD (VG) 2008-03-26 CN disclosed
CN-101147724-A Medicine or sanitary product containing licorice flavone extraction for oral cavity HAOWEI CO LTD (VG) 2008-03-26 CN disclosed
EP-1644500-A2 POLYCATIONIC COMPOSITIONS FOR CELLULAR DELIVERY OF POLYNUCLEOTIDES Sirna Therapeutics, Inc. (US) 2006-04-12 EP disclosed
WO-2005007854-A2 POLYCATIONIC COMPOSITIONS FOR CELLULAR DELIVERY OF POLYNUCLEOTIDES SIRNA THERAPEUTICS, INC. (US) 2005-01-27 WO disclosed
EP-0449872-B1 ABSORBENT MATERIAL LAPORTE INDUSTRIES LTD (GB) 1995-07-26 EP disclosed
US-5109805-A Litter LAPORTE INDUSTRIES LIMITED (GB) 1992-05-05 US disclosed
EP-0449872-A1 ABSORBENT MATERIAL. LAPORTE INDUSTRIES LTD (GB) 1991-10-09 EP disclosed
WO-1990007273-A1 ABSORBENT MATERIAL LAPORTE INDUSTRIES LIMITED (GB) 1990-07-12 WO disclosed
US-4062793-A GUANIDO-HEXANES BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DT) 1977-12-13 US disclosed