Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.69 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897353 | 1.00 | P2RY12 (0.69) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4885638 | 0.91 | P2RY12 (0.82) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4894358 | 0.91 | P2RY12 (0.82) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4893721 | 0.89 | P2RY12 (0.67) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4919217 | 0.88 | P2RY12 (0.53) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4910828 | 0.88 | P2RY12 (0.53) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4922072 | 0.86 | P2RY12 (0.53) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4899024 | 0.86 | P2RY12 (0.68) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4893546 | 0.86 | P2RY12 (0.68) | P2RY12CNR2GPR55MEN1 | |
| SCHEMBL4910234 | 0.82 | P2RY12 (0.58) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194590-A1 | 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC | 2008-08-14 | — | — | US | disclosed |
| US-20080194590-A1 | 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC | 2008-08-14 | — | — | US | disclosed |
| US-20080194590-A1 | 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194590-A1 | 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFKP, PF4, P2RY4 | P2RY12 20/4885CNR2 715/4885GPR55 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.