SCHEMBL4897288

SCHEMBL4897288

FC(F)(F)c1cccc(C(F)(F)F)c1.FC(F)(F)c1cccc(C(F)(F)F)c1.F[B-](F)(F)F.F[B-](F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
MAPK1 P28482 1/20 0.58
ALDH1A1 P00352 1/20 0.52
CES2 O00748 1/20 0.52
MGLL Q99685 1/20 0.52
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
IDO1 P14902 3/20 0.47
HTR3E A5X5Y0 1/20 0.47
HTR3B O95264 1/20 0.47
HTR3A P46098 1/20 0.47
HTR3D Q70Z44 1/20 0.47
HTR3C Q8WXA8 1/20 0.47
NOTUM Q6P988 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2381607 1.00 TSHR (0.58) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL1493015 0.97 TSHR (0.56) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL62723 0.91 TSHR (0.67) TSHRMAPK1ALDH1A1CES2MGLL
Fluoride SCHEMBL30661872 0.88 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL28126330 0.88 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL5698952 0.88 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL30252943 0.88 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
Benzene SCHEMBL8568955 0.88 TSHR (0.67) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL30553105 0.88 TSHR (0.64) TSHRMAPK1ALDH1A1CES2MGLL
SCHEMBL8718176 0.86 TSHR (0.63) TSHRMAPK1ALDH1A1CES2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080044149-A1 Polymerizable Composition TOYO INK MFG. CO., LTD. (JP) 2008-02-21 US disclosed
EP-1816152-A1 POLYMERIZABLE COMPOSITION TOYO INK MFG. CO., LTD. (JP) 2007-08-08 EP disclosed