Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897315 | 1.00 | MET (0.47) | METHDAC1HTR2C | |
| SCHEMBL4891539 | 0.88 | MET (0.48) | METHDAC1 | |
| SCHEMBL4891530 | 0.88 | MET (0.48) | METHDAC1 | |
| SCHEMBL4888466 | 0.86 | MET (0.50) | METHDAC1 | |
| SCHEMBL4892852 | 0.85 | MET (0.49) | METHDAC1 | |
| SCHEMBL4892843 | 0.85 | MET (0.49) | METHDAC1 | |
| SCHEMBL3859940 | 0.84 | MET (0.49) | METHDAC1 | |
| SCHEMBL4899009 | 0.83 | MET (0.48) | METHDAC1 | |
| SCHEMBL3863415 | 0.81 | MET (0.67) | MET | |
| SCHEMBL4892101 | 0.81 | MET (0.45) | METHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280917-A1 | Nitrogen-Containing heterocyclyl ketones and methods of use | AMGEN INC. (US) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280917-A1 | Nitrogen-Containing heterocyclyl ketones and methods of use | HGF, HGFAC, MET | MET 3/4885HDAC1 1251/4885HTR2C 3371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.